|
A special breast cancer study was chosen for one of the 1998 Patient
Care Evaluation studies by the ACoS. It was designed to document
current methods of diagnosis, staging, treatment, disease control
and survival in three areas of breast cancer: (1) all male breast
cancer (of any histology and any stage); (2) female ductal carcinoma
in-situ (DCIS); and (3) female breast cancer of any histology with
a tumor size of T1mic (microscopic invasion) or T1a (tumor size
0.5 cm or less). However, the Cancer Registry at Del Sol Medical
Center was not formally organized until 1/2000. Since it was not
possible to do the 1999 PCE on 1998 cases, the Cancer Committee
decided to do this study as one of the year 2000 PCE studies on
1999 data because of the importance of early breast cancer among
our patient population.
The study will primarily address: (1) radiographic, pathologic,
and clinical factors in treatment choices for DCIS and T1mic or
T1a tumors; (2) the risk factors for local recurrence in DCIS, T1mic
and T1a cancers; (3) current radiotherapeutic practice for DCIS;
(4) guidelines for pathological assessment of margins, grade, and
size of tumor; and (5) disease presentations, trends, and treatment
of male breast cancer, with a particular focus on adjuvant therapy.
We have developed some preliminary answers to these questions and
on that basis we provided information that will contribute to the
NCDB collection of data on these issues. Some of the relevant facts
are briefly referred to below.
We were able to submit the additional PCE information (specialized
and detailed data not included on the normal cancer abstract) for
eight eligible cases: one Stage IV male breast cancer patient, three
cases of ductal carcinoma in-situ, two cases with the tumor stage
of T1mic, and two cases with a tumor stage of T1a. (A ninth case
was not eligible because there was no histological confirmation.)
Only one of these patients had a second primary maligancy, and that
was also a breast cancer. Most cases had ductal and/or intraductal
histologies, although one case of ductal with tubular carcinoma
was reported. In two cases, the pathology reported comedo patterns
(an indicator for local recurrence). Ethnographically, study patients
mirror the El Paso population in being 80% Hispanic and 20% Non-Hispanic.
All patients were reported as White. Age at diagnosis: one patient
in her 30's, one in her 40's, one in her 50's, one in her 60's,
and four patients in the 70's.
| Tumor |
Stage |
Treatment Summary |
Tx @Del Sol |
Surg Type |
Margins |
LN Dissection |
|
Female Breast Cancer, Early Stage
|
| IS |
Stg 0 |
Surgery only |
Surg |
Lumpectomy |
Neg |
No |
| IS |
Stg 0 |
Surg/Rad/Chem/Horm |
All |
Lumpectomy |
Neg |
No |
| IS |
Stg 2A |
Surg/Rad/Horm |
Rad |
Lumpectomy |
Neg |
Yes, +LNS |
| 1mic |
Stg 1 |
Surg/Rad/Horm |
All |
Lumpectomy |
Neg |
Yes |
| 1mic |
Stg 2B |
Surg/Rad |
All |
Lumpectomy |
Neg |
Yes, +LNS |
| 1a |
Stg 1 |
Surg/Rad |
All |
Lumpectomy |
Neg |
Yes |
| 1a |
Stg 1 |
Surg/Rad |
Rad |
Lumpectomy |
Neg |
Yes |
|
Male Breast Cancer Patient
|
| 4d |
Stg 3B |
Surg/Rad/Chem/Horm |
Surg/Rad |
Mastectomy |
Involved |
Yes, +LNS |
Although we will compare our data to national trends when it is
returned by the NCDB, we have done one study comparing the figures
on breast conservation therapy vs. mastectomy with the data in our
corporate database. We found that our lumpectomy/mastectomy ratio
was superior to both national and corporate figures. However, a
more refined study is being undertaken by our pathologist in collaboration
with a radiation oncologist. Although an initial view of the data
gathered above indicates treatment that meets current clinical pathway
standards, we are refining and specifying our data to the highest
degree possible to provide the detailed knowledge required for this
study and thus to obtain an accurate picture of early-stage breast
cancer management here.
We will also develop recommendations for the improvement of care
for patients with early-stage breast cancer. Current activities
for education and prevention have been distribution of materials
at four health fairs, at cancer screenings at the Del Sol Regional
Oncology Center, and at the hospital for the observance of Breast
Cancer Awareness Month in October.
|